ARG59075
anti-StAR antibody
anti-StAR antibody for Immunoprecipitation,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes StAR |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | StAR |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 64-285 of Human StAR (NP_000340.2). |
| 偶联标记 | Un-conjugated |
| 別名 | START domain-containing protein 1; Steroidogenic acute regulatory protein, mitochondrial; STARD1; StAR; StARD1 |
应用说明
| 预测反应性说明 | Mouse | ||||||
|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 35kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P49675 Human Steroidogenic acute regulatory protein, mitochondrial Swiss-port # P51557 Mouse Steroidogenic acute regulatory protein, mitochondrial |
|---|---|
| 基因名称 | STAR |
| 全名 | steroidogenic acute regulatory protein |
| 背景介绍 | The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. [UniProt] |
| 细胞定位 | Mitochondrion. [UniProt] |
| 预测分子量 | 32 kDa |
