ARG56156
anti-Spred 1 antibody
anti-Spred 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Spred 1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 特异性 | This Spred1 antibody is predicted to have no cross-reactivity to Spred2 or Spred3. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Spred 1 |
| 抗原 | Synthetic peptide (14 aa) within aa. 250-300 of Human Spred1. |
| 偶联标记 | Un-conjugated |
| 別名 | PPP1R147; NFLS; spred-1; hSpred1; Spred-1; Sprouty-related, EVH1 domain-containing protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Human brain tissue lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q7Z699 Human Sprouty-related, EVH1 domain-containing protein 1 Swiss-port # Q924S8 Mouse Sprouty-related, EVH1 domain-containing protein 1 |
|---|---|
| 基因名称 | SPRED1 |
| 全名 | sprouty-related, EVH1 domain containing 1 |
| 背景介绍 | The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008] |
| 生物功能 | Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow (By similarity). [UniProt] |
| 预测分子量 | 50 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine. |
检测图片 (2) Click the Picture to Zoom In
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ARG56156 anti-Spred 1 antibody IHC-P image
Immunohistochemistry: Human brain tissue stained with ARG56156 anti-Spred 1 antibody at 2.5 µg/ml dilution.
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ARG56156 anti-Spred 1 antibody WB image
Western blot: Human brain tissue lysate stained with ARG56156 anti-Spred 1 antibody at (A) 1 and (B) 2 µg/ml dilution.
