ARG56324
anti-Splicing factor 1 antibody
anti-Splicing factor 1 antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Splicing factor 1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Splicing factor 1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human Splicing factor 1 |
| 偶联标记 | Un-conjugated |
| 別名 | Zinc finger gene in MEN1 locus; Zinc finger protein 162; ZNF162; ZFM1; Splicing factor 1; ZCCHC25; MBBP; Transcription factor ZFM1; D11S636; Mammalian branch point-binding protein; mBBP; BBP |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SF1 |
| 全名 | splicing factor 1 |
| 背景介绍 | This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| 生物功能 | Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor. [UniProt] |
| 预测分子量 | 68 kDa |
| 翻译后修饰 | Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463. |
检测图片 (1) Click the Picture to Zoom In
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ARG56324 anti-Splicing factor 1 antibody WB image
Western blot: HepG2 cell lysate stained with ARG56324 anti-Splicing factor 1 antibody.
