ARG58448
anti-Sp7 / Osterix antibody
anti-Sp7 / Osterix antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Sp7 / Osterix |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Gpig, Hrs, Rb |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Sp7 / Osterix |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C-terminal region of Human Sp7 / Osterix. (within the following sequence: RTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSP) |
| 偶联标记 | Un-conjugated |
| 別名 | Transcription factor Sp7; OI11; osterix; OSX; OI12; Zinc finger protein osterix |
应用说明
| 预测反应性说明 | Predicted homology based on immunogen sequence: Cow: 100%; Guinea Pig: 93%; Horse: 93%; Mouse: 92%; Rabbit: 86%; Rat: 93% | ||||
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| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Jurkat |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SP7 |
| 全名 | Sp7 transcription factor |
| 背景介绍 | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010] |
| 生物功能 | Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity). [UniProt] |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Ubiquitination at leads to proteasomal degradation. SP7 is a short-live protein with an endogenous half-life of approximately 12 hours. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG58448 anti-Sp7 / Osterix antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human intestine stained with ARG58448 anti-Sp7 / Osterix antibody.
