ARG22613
anti-Sodium / Hydrogen Exchanger 1 antibody [4E9]
anti-Sodium / Hydrogen Exchanger 1 antibody [4E9] for Western blot and Mouse,Rat,Fish,Pig,Rabbit
概述
| 产品描述 | Mouse Monoclonal antibody [4E9] recognizes Sodium / Hydrogen Exchanger 1 This antibody recognizes the Na+/H+ exchanger-1 (NHE1), a membrane protein involved in pH regulation and signal transduction.Mouse anti Porcine sodium/hydrogen exchanger 1 antibody, clone 4E9 recognizes NHE1 from the salamander Amphiuma tridactylum (McLean et al. 1999) and in the flounder Pseudopleuronectes americanus |
|---|---|
| 反应物种 | Ms, Rat, Fsh, Pig, Rb |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 4E9 |
| 同位型 | IgG1 |
| 靶点名称 | Sodium / Hydrogen Exchanger 1 |
| 抗原物种 | Pig |
| 抗原 | Maltose binding protein fusion protein containing the entire C-terminal, hydrophilic domain of porcine NHE1. |
| 偶联标记 | Un-conjugated |
| 別名 | Sodium/hydrogen exchanger 1; LIKNS; APNH; +; PPP1R143; Na; NHE-1; Solute carrier family 9 member 1; NHE1 |
应用说明
| 应用建议 |
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| 应用说明 | WB: OBT1655 detects a band of approximately 100 kDa in human kidney lysates. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 0.1% Sodium azide. |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SLC9A1 |
| 全名 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| 背景介绍 | This gene encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. The encoded protein is a plasma membrane transporter that is expressed in the kidney and intestine. This protein plays a central role in regulating pH homeostasis, cell migration and cell volume. This protein may also be involved in tumor growth. [provided by RefSeq, Sep 2011] |
| 生物功能 | Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. [UniProt] |
| 预测分子量 | 91 kDa |
| 翻译后修饰 | O-glycosylated. Ubiquitinated, leading to its degradation by the proteasome. Ubiquitination is reduced by CHP1 (By similarity). |
