ARG59877
anti-Slow Skeletal Myosin Heavy chain antibody [NOQ7.5.4D]
anti-Slow Skeletal Myosin Heavy chain antibody [NOQ7.5.4D] for ELISA,Electron microscopy,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Radioimmunoassay,Western blot and Human,Mouse,Rat,Rabbit
概述
| 产品描述 | Mouse Monoclonal antibody [NOQ7.5.4D] recognizes Slow Skeletal Myosin Heavy chain |
|---|---|
| 反应物种 | Hu, Ms, Rat, Rb |
| 应用 | ELISA, EM, ICC/IF, IHC-P, RIA, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | NOQ7.5.4D |
| 同位型 | IgG1 |
| 靶点名称 | Slow Skeletal Myosin Heavy chain |
| 抗原物种 | Human |
| 抗原 | Human skeletal muscle myosin purified from myofibrils. |
| 偶联标记 | Un-conjugated |
| 別名 | SPMD; MyHC-slow; SPMM; Myosin heavy chain 7; CMD1S; Myosin heavy chain, cardiac muscle beta isoform; MyHC-beta; MPD1; MYHCB; CMH1; Myosin heavy chain slow isoform; Myosin-7 |
应用说明
| 应用建议 |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Unpurified. |
| 缓冲液 | Ascites fluid, 1.2% Sodium acetate, 0.01% Sodium azide and 2% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 2% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MYH7 |
| 全名 | myosin, heavy chain 7, cardiac muscle, beta |
| 背景介绍 | Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008] |
| 生物功能 | Muscle contraction. [UniProt] |
| 细胞定位 | Cytoplasm, myofibril. Thick filaments of the myofibrils. [UniProt] |
| 预测分子量 | 223 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG59877 anti-Slow Skeletal Myosin Heavy chain antibody [NOQ7.5.4D] WB image
Western blot: 50 µg of samples under reducing conditions. Mouse skeletal muscle and Rat skeletal muscle lysates stained with ARG59877 anti-Slow Skeletal Myosin Heavy chain antibody [NOQ7.5.4D] at 0.5 μg/ml, overnight at 4°C.
