ARG67279
anti-Slow Skeletal Myosin Heavy chain antibody
anti-Slow Skeletal Myosin Heavy chain antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Monoclonal antibody recognizes Slow Skeletal Myosin Heavy chain |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 特异性 | The antibody detects endogenous Slow Skeletal Myosin Heavy chain protein. |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 同位型 | IgG,Kappa |
| 靶点名称 | Slow Skeletal Myosin Heavy chain |
| 偶联标记 | Un-conjugated |
| 別名 | MYH7; myosin, heavy chain 7, cardiac muscle, beta; SPMD; MyHC-slow; SPMM; Myosin heavy chain 7; CMD1S; Myosin heavy chain, cardiac muscle beta isoform; MyHC-beta; MPD1; MYHCB; CMH1; Myosin heavy chain slow isoform; Myosin-7 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A |
| 缓冲液 | PBS, 0.05% Proclin 300 , 50% glycerol and 0.05% BSA |
| 抗菌剂 | 0.05% Proclin 300 |
| 稳定剂 | 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MYH7 |
| 全名 | myosin, heavy chain 7, cardiac muscle, beta |
| 背景介绍 | Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis. [UniProt] |
| 细胞定位 | Cytoplasm, myofibril. Thick filaments of the myofibrils. [UniProt] |
| 预测分子量 | 223 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG67279 anti-Slow Skeletal Myosin Heavy chain antibody WB image
Western blot: Various whole cell lysate stained with ARG67279 anti-Slow Skeletal Myosin Heavy chain antibody.
