ARG45908
anti-Skeletrophin / Mib2 antibody
anti-Skeletrophin / Mib2 antibody for Western blot,Immunoprecipitation,Flow cytometry and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Skeletrophin / Mib2 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Skeletrophin / Mib2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human Skeletrophin / Mib2. |
| 偶联标记 | Un-conjugated |
| 別名 | MIB E3 Ubiquitin Protein Ligase 2; MIB2; SKD; ZZANK1; E3 ubiquitin-protein ligase MIB2; EC 2.3.2.27; Mind bomb homolog 2; Novel zinc finger protein; Novelzin; Putative NF-kappa-B-activating protein 002N; RING-type E3 ubiquitin transferase MIB2; Skeletrophin; Zinc finger ZZ type with ankyrin repeat domain protein 1 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 110 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MIB2 |
| 全名 | MIB E3 Ubiquitin Protein Ligase 2 |
| 背景介绍 | The protein encoded by this gene is an E3 ubiquitin protein ligase that mediates ubiquitination of proteins in the Notch signaling pathway. The encoded protein may be a suppressor of melanoma invasion. [provided by RefSeq, Mar 2017] |
| 生物功能 | E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. [UniProt] |
| 细胞定位 | Cytoplasm; Endosome. [UniProt] |
| 预测分子量 | 110 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
-
ARG45908 anti-Skeletrophin / Mib2 antibody WB image
Western blot: A431 stained with ARG45908 anti-Skeletrophin / Mib2 antibody at 0.5 μg/ml dilution.
-
ARG45908 anti-Skeletrophin / Mib2 antibody IP image
Immunoprecipitation: A431 lysate immunoprecipitated with 2 μg ARG45908 anti-Skeletrophin / Mib2 antibody.
-
ARG45908 anti-Skeletrophin / Mib2 antibody FACS image
Flow Cytometry: SiHa stained with ARG45908 anti-Skeletrophin / Mib2 antibody at 1 µg/10^6 cells dilution.
