ARG56008
anti-Semaphorin 4D antibody [A8]
anti-Semaphorin 4D antibody [A8] for Flow cytometry,ICC/IF and Human,Mouse
概述
| 产品描述 | Mouse Monoclonal antibody [A8] recognizes Semaphorin 4D |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | FACS, ICC/IF |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | A8 |
| 同位型 | IgG1, kappa |
| 靶点名称 | Semaphorin 4D |
| 抗原物种 | Human |
| 抗原 | PHA stimulated Human peripheral blood lymphocytes. |
| 偶联标记 | Un-conjugated |
| 別名 | CD100; GR3; CD antigen CD100; M-sema-G; BB18; C9orf164; SEMAJ; Semaphorin-4D; A8; coll-4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SEMA4D |
| 全名 | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| 生物功能 | Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA. [UniProt] |
| 细胞定位 | Cell surface |
| 预测分子量 | 96 kDa |
