ARG54106
anti-SWAP70 antibody
anti-SWAP70 antibody for Immunoprecipitation,Western blot and Human,Mouse,Rat,Monkey
Immune System antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody recognizes SWAP70 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Mk |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | SWAP70 |
| 抗原物种 | Human |
| 抗原 | Purified recombinant human SWAP70 protein fragments expressed in E.coli. |
| 偶联标记 | Un-conjugated |
| 別名 | SWAP-70; Switch-associated protein 70; HSPC321 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 70 kDa |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | Ascites |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SWAP70 |
| 全名 | SWAP switching B-cell complex 70kDa subunit |
| 背景介绍 | Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which,_x000D_ independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane_x000D_ ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated_x000D_ phosphatidylinositol (3,4)-bisphosphate production and cell protrusion |
| 生物功能 | Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm. Cell membrane. Nucleus. Cell projection, lamellipodium. |
| 研究领域 | Immune System antibody; Signaling Transduction antibody |
| 预测分子量 | 69 kDa |
| 翻译后修饰 | Tyrosine-phosphorylated. |
检测图片 (2) Click the Picture to Zoom In
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ARG54106 anti-SWAP70 antibody WB image
Western blot: 3T3 cell lysate stained with ARG54106 anti-SWAP70 antibody at 1:1000 dilution.
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ARG54106 anti-SWAP70 antibody IP image
Immunoprecipitation: HeLa cell lysates were immunoprecipitated and stained with ARG54106 anti-SWAP70 antibody.
