ARG66477

anti-SUPV3L1 / SUV3 antibody

anti-SUPV3L1 / SUV3 antibody for Western blot and Human,Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes SUPV3L1 / SUV3
反应物种 Hu, Ms
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 SUPV3L1 / SUV3
抗原物种 Human
抗原 Recombinant full length protein of Human SUPV3L1 / SUV3.
偶联标记 Un-conjugated
別名 SUPV3L1; SUV3; ATP-dependent RNA helicase SUPV3L1, mitochondrial; SUV3-like protein 1; EC 3.6.4.13; Suppressor of var1 3-like protein 1; SUV3L1

应用说明

应用建议
应用 推荐稀释比
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.42% Potassium phosphate (pH 7.3), 0.87% Sodium chloride, 0.01% Sodium azide and 30% Glycerol.
抗菌剂 0.87% Sodium chloride
稳定剂 0.01% Sodium azide and 30% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 338359 Mouse SUPV3L1

GeneID: 6832 Human SUPV3L1

Swiss-port # Q80YD1 Mouse ATP-dependent RNA helicase SUPV3L1, mitochondrial

Swiss-port # Q8IYB8 Human ATP-dependent RNA helicase SUPV3L1, mitochondrial

基因名称 SUPV3L1
全名 SUV3-like helicase
生物功能 Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. [UniProt]
细胞定位 Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid. [UniProt]
预测分子量 88 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG66477 anti-SUPV3L1 / SUV3 antibody WB image

    Western blot: K562, Jurkat, Mouse heart and Mouse liver whole cell lysates stained with ARG66477 anti-SUPV3L1 / SUV3 antibody.