ARG59818
anti-SUCLA2 antibody
anti-SUCLA2 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SUCLA2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SUCLA2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-180 of Human SUCLA2 (NP_003841.1). |
| 偶联标记 | Un-conjugated |
| 別名 | MTDPS5; SCS-betaA; Succinyl-CoA synthetase beta-A chain; A-BETA; EC 6.2.1.5; Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; Renal carcinoma antigen NY-REN-39; ATP-specific succinyl-CoA synthetase subunit beta |
应用说明
| 预测反应性说明 | Rat | ||||||
|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse heart and HeLa | ||||||
| 实际分子量 | 50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9P2R7 Human Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial Swiss-port # Q9Z2I9 Mouse Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial |
|---|---|
| 基因名称 | SUCLA2 |
| 全名 | succinate-CoA ligase, ADP-forming, beta subunit |
| 背景介绍 | Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes the ATP-dependent ligation of succinate and CoA to form succinyl-CoA. [UniProt] |
| 细胞定位 | Mitochondrion. [UniProt] |
| 预测分子量 | 50 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59818 anti-SUCLA2 antibody WB image
Western blot: 25 µg of Mouse heart and HeLa cell lysates stained wtih ARG59818 anti-SUCLA2 antibody at 1:1000 dilution.
