ARG45796
anti-STXBP2 antibody
anti-STXBP2 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes STXBP2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | STXBP2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to N-terminal region of human STXBP2. |
| 偶联标记 | Un-conjugated |
| 別名 | STXBP2; syntaxin binding protein 2; Protein unc-18 homolog B; UNC18-2; Unc-18B; MUNC18-2; Unc18-2; Protein unc-18 homolog 2; UNC18B; FHL5; pp10122; Hunc18b; Syntaxin-binding protein 2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 66 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | STXBP2 |
| 全名 | syntaxin binding protein 2 |
| 背景介绍 | This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013] |
| 生物功能 | Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. [UniProt] |
| 细胞定位 | Azurophil granule; Cytolytic granule; Cytosol; Extracellular region; Plasma membrane; Presynapse. [UniProt] |
| 预测分子量 | 66 kDa |
检测图片 (5) Click the Picture to Zoom In
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ARG45796 anti-STXBP2 antibody ICC/IF image
Immunofluorescence: SK-OV-3 stained with ARG45796 anti-STXBP2 antibody at 5 μg/ml dilution.
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ARG45796 anti-STXBP2 antibody WB image
Western blot: K562 stained with ARG45796 anti-STXBP2 antibody at 0.5 μg/ml dilution.
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ARG45796 anti-STXBP2 antibody FACS image
Flow Cytometry: U937 stained with ARG45796 anti-STXBP2 antibody at 1 µg/10^6 cells dilution.
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ARG45796 anti-STXBP2 antibody WB image
Western blot: Rat brain stained with ARG45796 anti-STXBP2 antibody at 0.5 μg/ml dilution.
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ARG45796 anti-STXBP2 antibody WB image
Western blot: Mouse brain stained with ARG45796 anti-STXBP2 antibody at 0.5 μg/ml dilution.
