ARG42643
anti-STS / Arylsulfatase C antibody
anti-STS / Arylsulfatase C antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes STS / Arylsulfatase C |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | STS / Arylsulfatase C |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to K297-E396 of Human STS / Arylsulfatase C. |
| 偶联标记 | Un-conjugated |
| 別名 | XLI; ARSC; Steroid sulfatase; SSDD; Steryl-sulfate sulfohydrolase; ASC; Steryl-sulfatase; Arylsulfatase C; EC 3.1.6.2; ARSC1; ES |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 65 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | STS |
| 全名 | steroid sulfatase (microsomal), isozyme S |
| 背景介绍 | This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726). [provided by RefSeq, Mar 2016] |
| 生物功能 | Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 65 kDa |
| 翻译后修饰 | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG42643 anti-STS / Arylsulfatase C antibody WB image
Western blot: 50 µg of samples under reducing conditions. HeLa, Human placenta, MCF7, HepG2 and PANC-1 whole cell lysates stained with ARG42643 anti-STS / Arylsulfatase C antibody at 0.5 µg/ml dilution, overnight at 4°C.
