ARG64221

anti-STRA antibody

anti-STRA antibody for Western blot and Mouse,Rat

Controls and Markers antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody

概述

产品描述 Goat Polyclonal antibody recognizes STRA
反应物种 Ms, Rat
应用 WB
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 STRA
抗原物种 Rat
抗原 C-QAFRKAALTSAKAN
偶联标记 Un-conjugated
別名 MCOPCB8; PP14296; Stimulated by retinoic acid gene 6 protein homolog; MCOPS9

应用说明

应用建议
应用 推荐稀释比
WB1 - 2 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 20897 Mouse STRA6

GeneID: 363071 Rat STRA6

Swiss-port # O70491 Mouse Stimulated by retinoic acid gene 6 protein

Swiss-port # Q4QR83 Rat Stimulated by retinoic acid gene 6 protein homolog

基因名称 Stra6
全名 stimulated by retinoic acid 6
背景介绍 The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
生物功能 May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity. Increases cellular retinol uptake from the retinol-RBP complex (By similarity). [UniProt]
研究领域 Controls and Markers antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody
预测分子量 74 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG64221 anti-STRA antibody WB image

    Western Blot: 3T3-L1 lysates (35 µg protein in RIPA buffer) stained with ARG64221 anti-STRA6 (mouse|rat) antibody at 1.7 µg/ml dilution.

  • ARG64221 anti-STRA antibody WB image

    Western blot: 35 µg of Rat testis lysate (in RIPA buffer) with (B) and without (A) blocking peptide. The blots were stained with ARG64221 anti-STRA antibody at 1 µg/ml dilution and incubated at RT for 1 hour.