ARG63628
anti-STMN2 / SCG10 antibody
anti-STMN2 / SCG10 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse
Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes STMN2 / SCG10 |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu, Rat, Cow, Dog |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | STMN2 / SCG10 |
| 抗原物种 | Human |
| 抗原 | AKTAMAYKEK-C |
| 偶联标记 | Un-conjugated |
| 別名 | Protein SCG10; SCG10; SCGN10; Stathmin-2; Superior cervical ganglion-10 protein |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 21 kDa |
| 翻译后修饰 | Sumoylated. Phosphorylated mostly by MAPK8, but also by MAPK9 and MAPK10 in the developing brain cortex. N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15. |
检测图片 (3) Click the Picture to Zoom In
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ARG63628 anti-STMN2 / SCG10 antibody WB image
Western Blot: Human Brain lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63628 anti-STMN2 / SCG10 antibody at 1 µg/ml dilution.
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ARG63628 anti-STMN2 / SCG10 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human small intestine tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63628 anti-STMN2 / SCG10 antibody at 5 µg/ml dilution followed by AP-staining.
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ARG63628 anti-STMN2 / SCG10 antibody WB image
Western blot: 35 µg of Mouse foetal brain lysate (in RIPA buffer) stained with ARG63628 anti-STMN2 / SCG10 antibody at 0.5 µg/ml dilution and incubated at RT for 1 hour.
