ARG64954

anti-STK39 / SPAK antibody

anti-STK39 / SPAK antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Metabolism antibody; Signaling Transduction antibody

概述

产品描述 Goat Polyclonal antibody recognizes STK39 / SPAK
反应物种 Hu, Ms, Rat
预测物种 Dog
应用 IHC-P, WB
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 STK39 / SPAK
抗原物种 Human
抗原 C-SQEKSRRVKEENPE
偶联标记 Un-conjugated
別名 SPAK; STE20/SPS1-related proline-alanine-rich protein kinase; Ste-20-related kinase; Serine/threonine-protein kinase 39; EC 2.7.11.1; PASK; DCHT

应用说明

应用建议
应用 推荐稀释比
IHC-P3 - 5 µg/ml
WB0.3 - 1 µg/ml
应用说明 IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 27347 Human STK39

GeneID: 53416 Mouse STK39

GeneID: 54348 Rat STK39

背景介绍 This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]
研究领域 Metabolism antibody; Signaling Transduction antibody
预测分子量 59 kDa
翻译后修饰 Phosphorylated at Ser-309 by PRKCQ.

检测图片 (3) Click the Picture to Zoom In

  • ARG64954 anti-STK39 / SPAK antibody WB image

    Western Blot: Jurkat lysate (35 µg protein in RIPA buffer) stained with ARG64954 anti-STK39 / SPAK antibody at 0.5 µg/ml dilution.

  • ARG64954 anti-STK39 / SPAK antibody WB image

    Western Blot: Mouse (A) and Rat (B) Brain (35 µg protein in RIPA buffer) stained with ARG64954 anti-STK39 / SPAK antibody at 1 µg/ml dilution.

  • ARG64954 anti-STK39 / SPAK antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Cerebral Cortex. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64954 anti-STK39 / SPAK antibody at 3.8 µg/ml dilution followed by AP-staining.