ARG51555
anti-STAT6 phospho (Thr645) antibody
anti-STAT6 phospho (Thr645) antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Gene Regulation antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes STAT6 phospho (Thr645) |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | STAT6 |
| 抗原物种 | Human |
| 抗原 | Peptide sequence around phosphorylation site of threonine 645 (P-A-T(p)-I-K) derived from Human STAT6. |
| 偶联标记 | Un-conjugated |
| 別名 | D12S1644; STAT6B; STAT6C; Signal transducer and activator of transcription 6; IL-4-STAT; IL-4 Stat |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antibodies were produced by immunizing rabbits with KLH-conjugated synthetic phosphopeptide. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. In addition, non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 缓冲液 | PBS (without Mg2+ and Ca2+, pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P42226 Human Signal transducer and activator of transcription 6 |
|---|---|
| 基因名称 | STAT6 |
| 全名 | signal transducer and activator of transcription 6, interleukin-4 induced |
| 背景介绍 | Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling. |
| 生物功能 | Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. [UniProt] |
| 研究领域 | Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 94 kDa |
| 翻译后修饰 | Tyrosine phosphorylated following stimulation by IL4/interleukin-4 and IL3/interleukin-3 (By similarity). Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling. |
检测图片 (2) Click the Picture to Zoom In
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ARG51555 anti-STAT6 phospho (Thr645) antibody WB image
Western blot: Extracts from HeLa cells, treated with IL-4 or calf intestinal phosphatase (CIP), stained with ARG51555 anti-STAT6 phospho (Thr645) antibody.
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ARG51555 anti-STAT6 phospho (Thr645) antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human breast carcinoma tissue stained with ARG51555 anti-STAT6 phospho (Thr645) antibody (left) or the same antibody preincubated with blocking peptide (right).
