ARG57805
anti-STAB2 antibody
anti-STAB2 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes STAB2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | STAB2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1550-1850 of Human STAB2 (NP_060034.9). |
| 偶联标记 | Un-conjugated |
| 別名 | FEX2; FELE-2; HARE; Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; Hyaluronan receptor for endocytosis; FEEL-2; Stabilin-2; FELL2; FEEL2; 190 kDa hyaluronan receptor for endocytosis; FAS1 EGF-like and X-link domain-containing adhesion molecule 2 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse liver | ||||
| 实际分子量 | ~ 277 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | STAB2 |
| 全名 | stabilin 2 |
| 背景介绍 | This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008] |
| 生物功能 | Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS. [UniProt] |
| 细胞定位 | Cell membrane, Single-pass type I membrane protein, Cytoplasm. [UniProt] |
| 预测分子量 | 277 kDa |
| 翻译后修饰 | Glycosylated. Proteolytically processed to yield a 190 kDa protein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
-
ARG57805 anti-STAB2 antibody WB image
Western blot: 25 µg of Mouse liver lysate stained with ARG57805 anti-STAB2 antibody at 1:1000 dilution.
