ARG45655
anti-SSX2IP antibody
anti-SSX2IP antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SSX2IP |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SSX2IP |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human SSX2IP. |
| 偶联标记 | Un-conjugated |
| 別名 | SSX2IP; SSX Family Member 2 Interacting Protein; HMsd1; Synovial Sarcoma, X Breakpoint 2 Interacting Protein; Afadin- And Alpha-Actinin-Binding Protein; Afadin DIL Domain-Interacting Protein; SSX2-Interacting Protein; ADIP; KIAA0923 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 71 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8CGZ2 Rat Afadin- and alpha-actinin-binding protein Swiss-port # Q9Y2D8 Human Afadin- and alpha-actinin-binding protein |
|---|---|
| 基因名称 | SSX2IP |
| 全名 | SSX Family Member 2 Interacting Protein |
| 背景介绍 | This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009] |
| 生物功能 | Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. [UniProt] |
| 细胞定位 | Cell junction; Cell projection; Cytoplasm; Cytoskeleton; Nucleus. [UniProt] |
| 预测分子量 | 71 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45655 anti-SSX2IP antibody IHC-P image
Immunohistochemistry: Human cervix squamous cell carcinoma stained with ARG45655 anti-SSX2IP antibody at 2 μg/ml dilution.
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ARG45655 anti-SSX2IP antibody WB image
Western blot: K562 stained with ARG45655 anti-SSX2IP antibody at 0.5 μg/ml dilution.
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ARG45655 anti-SSX2IP antibody FACS image
Flow Cytometry: U251 stained with ARG45655 anti-SSX2IP antibody at 1 µg/10^6 cells dilution.
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ARG45655 anti-SSX2IP antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45655 anti-SSX2IP antibody at 2 μg/ml dilution.
