ARG57748
anti-SSTR1 antibody
anti-SSTR1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SSTR1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SSTR1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around aa. 361-381 (RAYSVEDFQPENLESGGVFRN) of Human SSTR1. (100% homologous in Human, Mouse and Rat). |
| 偶联标记 | Un-conjugated |
| 別名 | SRIF-2; SS-1-R; SS1R; Somatostatin receptor type 1; SS1-R |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in Citrate buffer (pH 6.0) for 20 min, followed by cooling at RT. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 实际分子量 | 42 kDa ~ 80 kDa due to glycosylation. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.025% Sodium azide and 2.5% BSA. |
| 抗菌剂 | 0.025% Sodium azide |
| 稳定剂 | 2.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SSTR1 |
| 全名 | somatostatin receptor 1 |
| 背景介绍 | Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012] |
| 生物功能 | Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. [UniProt] |
| 预测分子量 | 43 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG57748 anti-SSTR1 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Rat intestine tissue stained with ARG57748 anti-SSTR1 antibody at 1 µg/ml. Antigen Retrieval: Boil tissue section in Citrate buffer (pH 6.0) for 20 min followed by cooling at RT.
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ARG57748 anti-SSTR1 antibody WB image
Western blot: Rat intestine lysate stained with ARG57748 anti-SSTR1 antibody.
