ARG65308
anti-SRGAP2 antibody
anti-SRGAP2 antibody for ICC/IF,Western blot and Human,Rat
Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes SRGAP2 |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms, Cow, Dog |
| 应用 | ICC/IF, WB |
| 特异性 | This antibody is expected to recognize isoform a (NP_056141.2). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SRGAP2 |
| 抗原物种 | Human |
| 抗原 | C-KQEDRQTPRSPDST |
| 偶联标记 | Un-conjugated |
| 別名 | FNBP2; SRGAP3; srGAP2; ARHGAP34; SLIT-ROBO Rho GTPase-activating protein 2; Formin-binding protein 2; Rho GTPase-activating protein 34; SRGAP2A |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # D4A208 Rat SLIT-ROBO Rho GTPase-activating protein 2 Swiss-port # O75044 Human SLIT-ROBO Rho GTPase-activating protein 2 |
|---|---|
| 背景介绍 | This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014] |
| 研究领域 | Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 121 kDa |
| 翻译后修饰 | Methylation at Arg-927 is required for the stimulation of cell migration, dimerization and localization at the plasma membrane protrusions. |
检测图片 (1) Click the Picture to Zoom In
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ARG65308 anti-SRGAP2 antibody WB image
Western blot: 35 µg of Rat cortical neuron lysate stained with ARG65308 anti-SRGAP2 antibody at 0.1 µg/ml dilution and incubated for 1 hour.
