ARG45733
anti-SPTBN2 antibody
anti-SPTBN2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SPTBN2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SPTBN2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human SPTBN2. |
| 偶联标记 | Un-conjugated |
| 別名 | SPTBN2; Spectrin Beta, Non-Erythrocytic 2; SCA5; Spectrin Beta Chain, Non-Erythrocytic 2; Spinocerebellar Ataxia 5 Protein; Beta-III Spectrin; Glutamate Transporter EAAT4-Associated Protein 41; Spectrin, Non-Erythroid Beta Chain 2; Spectrin Beta Chain, Brain 2; Spectrin Beta III Sigma 2; Spinocerebellar Ataxia 5; KIAA0302; GTRAP41; SCAR14 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 271 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O15020 Human Spectrin beta chain, non-erythrocytic 2 Swiss-port # Q9QWN8 Rat Spectrin beta chain, non-erythrocytic 2 |
|---|---|
| 基因名称 | SPTBN2 |
| 全名 | Spectrin Beta, Non-Erythrocytic 2 |
| 背景介绍 | Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009] |
| 生物功能 | Probably plays an important role in neuronal membrane skeleton. . [UniProt] |
| 细胞定位 | Cytoplasm; Cytoskeleton. [UniProt] |
| 预测分子量 | 271 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45733 anti-SPTBN2 antibody WB image
Western blot: Hela stained with ARG45733 anti-SPTBN2 antibody at 0.5 μg/ml dilution.
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ARG45733 anti-SPTBN2 antibody FACS image
Flow Cytometry: Jurkat stained with ARG45733 anti-SPTBN2 antibody at 1 µg/10^6 cells dilution.
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ARG45733 anti-SPTBN2 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45733 anti-SPTBN2 antibody at 2 μg/ml dilution.
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ARG45733 anti-SPTBN2 antibody WB image
Western blot: Rat brain stained with ARG45733 anti-SPTBN2 antibody at 0.5 μg/ml dilution.
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ARG45733 anti-SPTBN2 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45733 anti-SPTBN2 antibody at 2 μg/ml dilution.
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ARG45733 anti-SPTBN2 antibody WB image
Western blot: Mouse brain stained with ARG45733 anti-SPTBN2 antibody at 0.5 μg/ml dilution.
