ARG46522
anti-SPRED3 antibody
anti-SPRED3 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SPRED3 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SPRED3 |
| 抗原物种 | Human |
| 抗原 | A 16 amino acid synthetic peptide within the last 50 amino acids of human SPRED3. |
| 偶联标记 | Un-conjugated |
| 別名 | sprouty-related, EVH1 domain containing 3; Spred3; Eve-3; spred-3; EVE-3; Sprouty-related; EVH1 domain-containing protein 3; Spred-3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 45 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -572°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q2MJR0 Human Sprouty-related, EVH1 domain-containing protein 3 |
|---|---|
| 基因名称 | SPRED3 |
| 全名 | sprouty-related, EVH1 domain containing 3 |
| 背景介绍 | This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen-activated protein (MAP) kinase signaling, particularly during organogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
| 生物功能 | Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (By similarity). Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity). [UniProt] |
| 细胞定位 | Cell membrane. [UniProt] |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Phosphoprotein; Ubl conjugation; Lipoprotein; Palmitate; Methylation. [UniProt] |
