ARG45726
anti-SPG3A / ATL1 antibody
anti-SPG3A / ATL1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SPG3A / ATL1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SPG3A / ATL1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to middle region of human SPG3A / ATL1. |
| 偶联标记 | Un-conjugated |
| 別名 | ATL1; Atlastin GTPase 1; AD-FSP; SPG3A; FSP1; Guanine Nucleotide-Binding Protein 3; Brain-Specific GTP-Binding Protein; Spastic Paraplegia 3 Protein A; GTP-Binding Protein 3; Atlastin-1; GBP-3; HGBP3; GBP3; SPG3; Spastic Paraplegia 3A (Autosomal Dominant); Guanylate-Binding Protein 3; EC 3.6.5.-; Atlastin1; Atlastin; HSN1D |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 64 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ATL1 |
| 全名 | Atlastin GTPase 1 |
| 背景介绍 | The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. [UniProt] |
| 细胞定位 | Cell projection; Endoplasmic reticulum; Golgi apparatus; Membrane. [UniProt] |
| 预测分子量 | 64 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45726 anti-SPG3A / ATL1 antibody IHC-P image
Immunohistochemistry: Human adenocarcinoma of the right colon stained with ARG45726 anti-SPG3A / ATL1 antibody at 2 μg/ml dilution.
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ARG45726 anti-SPG3A / ATL1 antibody WB image
Western blot: 293T stained with ARG45726 anti-SPG3A / ATL1 antibody at 0.5 μg/ml dilution.
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ARG45726 anti-SPG3A / ATL1 antibody FACS image
Flow Cytometry: U87 stained with ARG45726 anti-SPG3A / ATL1 antibody at 1 µg/10^6 cells dilution.
