ARG55931
anti-SOX4 antibody
anti-SOX4 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SOX4 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SOX4 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 86-114 (N-terminus) of Human SOX4. |
| 偶联标记 | Un-conjugated |
| 別名 | Transcription factor SOX-4; EVI16 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SOX4 |
| 全名 | SRY (sex determining region Y)-box 4 |
| 背景介绍 | This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008] |
| 生物功能 | Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif. [UniProt] |
| 细胞定位 | Nucleus |
| 预测分子量 | 47 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG55931 anti-SOX4 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human brain stained with ARG55931 anti-SOX4 antibody.
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ARG55931 anti-SOX4 antibody FACS image
Flow Cytometry: A2058 cells stained with ARG55931 anti-SOX4 antibody (right histogram) or without primary antibody control (left histogram), followed by incubation with FITC labelled secondary antibody.
