ARG55208
anti-SOX2 antibody
anti-SOX2 antibody for Western blot and Human,Mouse
Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SOX2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SOX2 |
| 抗原物种 | Mouse |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 6-39 (N-terminus) of Mouse SOX2. |
| 偶联标记 | Un-conjugated |
| 別名 | Transcription factor SOX-2; MCOPS3; ANOP3 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | NCCIT |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Sox2 |
| 全名 | SRY (sex determining region Y)-box 2 |
| 生物功能 | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). [UniProt] |
| 细胞定位 | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:17097055} |
| 研究领域 | Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody |
| 预测分子量 | 34 kDa |
| 翻译后修饰 | Sumoylation inhibits binding on DNA and negatively regulates the FGF4 transactivation. |
检测图片 (1) Click the Picture to Zoom In
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ARG55208 anti-SOX2 antibody WB image
Western blot: 20 µg of NCCIT cell lysate stained with ARG55208 anti-SOX2 antibody at 1:1000 dilution.
