ARG44587

anti-SOX2 antibody

anti-SOX2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

概述

产品描述 Rabbit Monoclonal antibody recognizes SOX2
反应物种 Hu, Ms
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Monoclonal
同位型 IgG
靶点名称 SOX2
抗原物种 Human
抗原 Synthetic peptide corresponding to internal region of human SOX2.
偶联标记 Un-conjugated
別名 SOX2; SRY-Box Transcription Factor 2; SRY (Sex Determining Region Y)-Box 2; Transcription Factor SOX-2; SRY-Box 2; Sex Determining Region Y-Box 2; SRY-Related HMG-Box Gene 2; Transcription Factor SOX2; MCOPS3; ANOP3

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50-1:200
IHC-P1:50-1:100
WB1:500-1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity Purified
缓冲液 PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 20674 Mouse SOX2

GeneID: 6657 Human SOX2

Swiss-port # P48431 Human Transcription factor SOX-2

Swiss-port # P48432 Mouse Transcription factor SOX-2

基因名称 SOX2
全名 SRY-Box Transcription Factor 2
背景介绍 This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
生物功能 Critical for early embryogenesis and for embryonic stem cell pluripotency.
May function as a switch in neuronal development. [UniProt]
细胞定位 Cytoplasm, Nucleus. [UniProt]
预测分子量 34 kDa

检测图片 (3) Click the Picture to Zoom In

  • ARG44587 anti-SOX2 antibody IHC-P image

    Immunohistochemistry: Human cervix carcinoma stained with ARG44587 anti-SOX2 antibody.

  • ARG44587 anti-SOX2 antibody ICC/IF image

    Immunofluorescence: NCCIT stained with ARG44587 anti-SOX2 antibody.

  • ARG44587 anti-SOX2 antibody WB image

    Western blot: F9 stained with ARG44587 anti-SOX2 antibody.