ARG56132
anti-SOX17 antibody
anti-SOX17 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SOX17 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 特异性 | This antibody is Human, Mouse and Rat reactive. SOX17 is predicted to not cross-react with other SOX proteins. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SOX17 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (16 aa) within aa. 240-290 of Human SOX17. |
| 偶联标记 | Un-conjugated |
| 別名 | VUR3; Transcription factor SOX-17 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HepG2 cell lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SOX17 |
| 全名 | SRY (sex determining region Y)-box 17 |
| 背景介绍 | This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008] |
| 生物功能 | Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity). [UniProt] |
| 预测分子量 | 44 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG56132 anti-SOX17 antibody IF image
Immunofluorescence: Mouse liver tissue stained with ARG56132 anti-SOX17 antibody at 20 µg/ml dilution.
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ARG56132 anti-SOX17 antibody WB image
Western blot: HepG2 cell lysate stained with ARG56132 anti-SOX17 antibody at (A) 0.5 and (B) 1 µg/ml dilution.
