ARG64790
anti-SOCS7 antibody
anti-SOCS7 antibody for Western blot and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes SOCS7 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SOCS7 |
| 抗原物种 | Human |
| 抗原 | C-DAGRKPKLTRTQS |
| 偶联标记 | Un-conjugated |
| 別名 | NAP4; Suppressor of cytokine signaling 7; SOCS-7; Nck, Ash and phospholipase C gamma-binding protein; NAP-4; Nck-associated protein 4; NCKAP4 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O14512 Human Suppressor of cytokine signaling 7 |
|---|---|
| 基因名称 | SOCS7 |
| 全名 | suppressor of cytokine signaling 7 |
| 生物功能 | Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 63 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG64790 anti-SOCS7 antibody WB image
Western Blot: Daudi lysate (35 µg protein in RIPA buffer) stained with ARG64790 anti-SOCS7 antibody at 1 µg/ml dilution.
