ARG63919

anti-SNX9 antibody

anti-SNX9 antibody for ICC/IF and Human

Signaling Transduction antibody

概述

产品描述 Goat Polyclonal antibody recognizes SNX9
反应物种 Hu
预测物种 Ms, Dog
应用 ICC/IF
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 SNX9
抗原物种 Human
抗原 C-HKGAIEKVKESDK
偶联标记 Un-conjugated
別名 SDP1; SH3 and PX domain-containing protein 3A; SH3PX1; WISP; Sorting nexin-9; SH3 and PX domain-containing protein 1; Protein SDP1; SH3PXD3A

应用说明

应用建议
应用 推荐稀释比
ICC/IF10 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 51429 Human SNX9

Swiss-port # Q9Y5X1 Human Sorting nexin-9

背景介绍 This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein. [provided by RefSeq, Jul 2008]
研究领域 Signaling Transduction antibody
预测分子量 67 kDa
翻译后修饰 Ubiquitinated by ITCH.
Phosphorylated on tyrosine residues by TNK2. Phosphorylation promotes its activity in the degradation of EGFR.

检测图片 (1) Click the Picture to Zoom In

  • ARG63919 anti-SNX9 antibody ICC/IF image

    Immunofluorescence: Paraformaldehyde fixed U2OS cells permeabilized with 0.15% Triton. Cells were stained with ARG63919 anti-SNX9 antibody (green) at 10 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Negative control: Unimmunized goat IgG (green) at 10 µg/ml dilution.