ARG45275
anti-SNX6 antibody
anti-SNX6 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Polyclonal antibody recognizes SNX6 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SNX6 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human SNX6. |
| 偶联标记 | Un-conjugated |
| 別名 | SNX6; Sorting Nexin 6; TRAF4-Associated Factor 2; Sorting Nexin-6; Tumor Necrosis Factor Receptor-Associated Factor 4(TRAF4)-Associated Factor 2; MSTP010; TFAF2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 47 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SNX6 |
| 全名 | Sorting Nexin 6 |
| 背景介绍 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate (Probable). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. [UniProt] |
| 细胞定位 | Cytoplasm; Cytoplasmic vesicle; Endosome; Membrane; Nucleus. [UniProt] |
| 预测分子量 | 47 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45275 anti-SNX6 antibody ICC/IF image
Immunofluorescence: U20S stained with ARG45275 anti-SNX6 antibody at 5 ug/ml dilution.
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ARG45275 anti-SNX6 antibody WB image
Western blot: A549 stained with ARG45275 anti-SNX6 antibody at 0.5 μg/ml dilution.
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ARG45275 anti-SNX6 antibody FACS image
Flow Cytometry: HCT116 stained with ARG45275 anti-SNX6 antibody at 1 µg/10^6 cells dilution.
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ARG45275 anti-SNX6 antibody WB image
Western blot: Rat brain and C6 stained with ARG45275 anti-SNX6 antibody at 0.5 μg/ml dilution.
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ARG45275 anti-SNX6 antibody WB image
Western blot: Mouse brain and RAW264.7 stained with ARG45275 anti-SNX6 antibody at 0.5 μg/ml dilution.
