ARG42786
anti-SNX4 antibody
anti-SNX4 antibody for Flow cytometry,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SNX4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SNX4 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human SNX4. |
| 偶联标记 | Un-conjugated |
| 別名 | Sorting nexin-4; ATG24B |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | NIH/3T3 | ||||||||
| 实际分子量 | ~ 54 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SNX4 |
| 全名 | sorting nexin 4 |
| 背景介绍 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012] |
| 生物功能 | Involved in the regulation of endocytosis and in several stages of intracellular trafficking (PubMed:12668730). Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. [UniProt] |
| 细胞定位 | Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also detected on a juxtanuclear endocytic recycling compartment (ERC). [UniProt] |
| 预测分子量 | 52 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG42786 anti-SNX4 antibody WB image
Western blot: NIH/3T3 cell lysate stained with ARG42786 anti-SNX4 antibody at 1:1000 dilution.
