ARG59483
anti-SMYD3 antibody
anti-SMYD3 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SMYD3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SMYD3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human SMYD3. |
| 偶联标记 | Un-conjugated |
| 別名 | KMT3E; ZNFN3A1; ZMYND1; bA74P14.1; EC 2.1.1.43; SET and MYND domain-containing protein 3; Histone-lysine N-methyltransferase SMYD3; Zinc finger MYND domain-containing protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||||
| 阳性对照 | HeLa | ||||||||||||
| 实际分子量 | ~ 42 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9CWR2 Mouse Histone-lysine N-methyltransferase SMYD3 Swiss-port # Q9H7B4 Human Histone-lysine N-methyltransferase SMYD3 |
|---|---|
| 基因名称 | SMYD3 |
| 全名 | SET and MYND domain containing 3 |
| 背景介绍 | This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| 生物功能 | Histone methyltransferase. Specifically methylates 'Lys-4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus. Note=Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M. [UniProt] |
| 预测分子量 | 49 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59483 anti-SMYD3 antibody WB image
Western blot: HeLa cell lysate stained with ARG59483 anti-SMYD3 antibody.
