ARG22356

anti-SMO / Smoothened Homolog antibody

anti-SMO / Smoothened Homolog antibody for Western blot and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes SMO / Smoothened Homolog
反应物种 Hu
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 SMO / Smoothened Homolog
抗原物种 Human
抗原 Synthetic peptide of Human SMO / Smoothened Homolog.
偶联标记 Un-conjugated
別名 Gx; SMO; Protein Gx; Smoothened homolog; FZD11; SMOH

应用说明

应用建议
应用 推荐稀释比
WB5 - 10 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Human brain.

属性

形式 Liquid
纯化 Ammonium sulfate precipitation.
缓冲液 PBS and 0.08% Sodium azide.
抗菌剂 0.08% Sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 6608 Human SMO

Swiss-port # Q99835 Human Smoothened homolog

基因名称 SMO
全名 smoothened, frizzled class receptor
背景介绍 The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010]
生物功能 G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia. [UniProt]
预测分子量 86 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG22356 anti-SMO / Smoothened Homolog antibody WB image

    Western blot: 15 µg of Human brain lysate stained with ARG22356 anti-SMO / Smoothened Homolog antibody at 1) 10 µg/ml, and 2) 5 µg/ml dilution.