ARG45169
anti-SMC4 antibody
anti-SMC4 antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SMC4 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SMC4 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human SMC4. |
| 偶联标记 | Un-conjugated |
| 別名 | SMC4; structural maintenance of chromosomes 4; Structural maintenance of chromosomes protein 4; SMC protein 4; SMC-4; Chromosome-associated polypeptide C; hCAP-C; XCAP-C homolog; SMC4; CAPC, SMC4L1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 180 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9NTJ3 Human Structural maintenance of chromosomes protein 4 |
|---|---|
| 基因名称 | SMC4 |
| 全名 | structural maintenance of chromosomes 4 |
| 背景介绍 | This gene belongs to the 'structural maintenance of chromosomes' (SMC) gene family. Members of this gene family play a role in two changes in chromosome structure during mitotic segregation of chromosomes- chromosome condensation and sister chromatid cohesion. The protein encoded by this gene is likely a subunit of the 13S condensin complex, which is involved in chromosome condensation. A pseudogene related to this gene is located on chromosome 2. [provided by RefSeq, Jun 2016] |
| 生物功能 | Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. [UniProt] |
| 细胞定位 | Nucleus; Cytoplasm; Chromosome. [UniProt] |
| 预测分子量 | 147 kDa |
| 翻译后修饰 | . [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45169 anti-SMC4 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45169 anti-SMC4 antibody at 2 ug/ml dilution.
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ARG45169 anti-SMC4 antibody WB image
Western blot: Hela, MDA-MB-453, A549, and Caco-2 stained with ARG45169 anti-SMC4 antibody at 0.5 μg/ml dilution.
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ARG45169 anti-SMC4 antibody FACS image
Flow Cytometry: HL-60 stained with ARG45169 anti-SMC4 antibody at 1 µg/10^6 cells dilution.
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ARG45169 anti-SMC4 antibody WB image
Western blot: COS-7 stained with ARG45169 anti-SMC4 antibody at 0.5 μg/ml dilution.
