ARG42034
anti-SLC7A11 / xCT antibody
anti-SLC7A11 / xCT antibody for Western blot and Human,Mouse,Rat
Ferroptosis/Oxytosis Study antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SLC7A11 / xCT |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SLC7A11 / xCT |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 150-250 of Human SLC7A11 (NP_055146.1). |
| 偶联标记 | Un-conjugated |
| 別名 | xCT; CCBR1; Cystine/glutamate transporter; Solute carrier family 7 member 11; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse liver | ||||
| 实际分子量 | ~ 37 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SLC7A11 |
| 全名 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| 背景介绍 | This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011] |
| 生物功能 | Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. [UniProt] |
| 细胞定位 | Membrane; Multi-pass membrane protein. [UniProt] |
| 产品亮点 | Related products: SLC7A11 antibodies; SLC7A11 Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: Ferroptosis/Oxytosis Antibody Panel is launched Therapeutic strategies against PDAC |
| 研究领域 | Ferroptosis/Oxytosis Study antibody |
| 预测分子量 | 55 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG42034 anti-SLC7A11 / xCT antibody WB image
Western blot: 25 µg of Mouse liver lysate stained with ARG42034 anti-SLC7A11 / xCT antibody at 1:1000 dilution.
