ARG43456
anti-SLC29A3 / ENT3 antibody
anti-SLC29A3 / ENT3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SLC29A3 / ENT3 |
|---|---|
| 反应物种 | Ms, Rat |
| 预测物种 | Hu |
| 应用 | IHC-P, WB |
| 特异性 | This SLC29A3 / ENT antibody is predicted to not cross-react with other SLC29 proteins. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SLC29A3 / ENT3 |
| 抗原物种 | Human |
| 抗原 | A 19 amino acid peptide within aa. N-terminal of Human SLC29A3 / ENT3. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Equilibrative nucleoside transporter 3 |
| 別名 | Equilibrative nucleoside transporter 3; ENT3; HJCD; PHID; HCLAP; Solute carrier family 29 member 3; UNQ717/PRO1380; hENT3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 50-70 kDa (70 kda might be protein with PTM) |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q80WK7 Rat Equilibrative nucleoside transporter 3 Swiss-port # Q99P65 Mouse Equilibrative nucleoside transporter 3 |
|---|---|
| 基因名称 | SLC29A3 |
| 全名 | solute carrier family 29 member 3 |
| 背景介绍 | This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2010] |
| 生物功能 | Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine, as well as several nucleoside analog drugs, such as anticancer and antiviral agents, including cladribine, cordycepin, tubercidin and AZT. Does not transport hypoxanthine.[provided by uniprot] |
| 细胞定位 | Endosome, Lysosome, Membrane |
| 预测分子量 | 51.8 kDa |
| 翻译后修饰 | Glycoprotein, Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG43456 anti-SLC29A3 / ENT3 antibody IHC-P image
Immunofluorescence: Paraffin-embedded Rat colon muscle tissue stained with ARG43456 anti-SLC29A3 / ENT3 antibody at 20 µg/ml dilution.
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ARG43456 anti-SLC29A3 / ENT3 antibody WB image
Western blot: Mouse bladder tissue lysate stained with ARG43456 anti-SLC29A3 / ENT3 antibody at 1 or 2 µg/ml dilution and incubated at RT for 1 hour, in 5% NFDM/TBST.
