ARG46494
anti-SLC29A2 / ENT2 antibody
anti-SLC29A2 / ENT2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SLC29A2 / ENT2 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SLC29A2 / ENT2 |
| 抗原物种 | Human |
| 抗原 | A 19 amino acid synthetic peptide within the last 50 amino acids of human SLC29A2 / ENT2. |
| 偶联标记 | Un-conjugated |
| 別名 | SLC29A2; Solute carrier family 29 member 2; Nucleoside transporter, ei-type; 36 kDa nucleolar protein HNP36; DER12; Hydrophobic nucleolar protein, 36 kDa; Delayed-early response protein 12; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; ENT2; Equilibrative NBMPR-insensitive nucleoside transporter; Equilibrative nucleoside transporter 2; HNP36 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 50 kDa |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q14542 Human Equilibrative nucleoside transporter 2 |
|---|---|
| 基因名称 | SLC29A2 |
| 全名 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| 背景介绍 | The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008] |
| 生物功能 | Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine. [UniProt] |
| 细胞定位 | Basolateral cell membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Localized at the basolateral cell membrane in polarized MDCK cells. [UniProt] |
| 预测分子量 | 50 kDa |
