ARG66890
anti-SLC26A3 / DRA antibody
anti-SLC26A3 / DRA antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SLC26A3 / DRA |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SLC26A3 / DRA |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from the C-terminal region of Human SLC26A3 / DRA. |
| 偶联标记 | Un-conjugated |
| 別名 | CLD; Chloride anion exchanger; Down-regulated in adenoma; DRA; Protein DRA; Solute carrier family 26 member 3 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | 293 and HeLa | ||||
| 实际分子量 | ~ 85 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SLC26A3 |
| 全名 | solute carrier family 26 (anion exchanger), member 3 |
| 背景介绍 | The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008] |
| 生物功能 | Chloride/bicarbonate exchanger. Mediates the efficient absorption of chloride ions in the colon, participating in fluid homeostasis. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt] |
| 细胞定位 | Apical cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Localized in sperm membranes. Midpiece of sperm tail. Colocalizes with CFTR at the midpiece of sperm tail (By similarity). [UniProt] |
| 预测分子量 | 85 kDa |
| 翻译后修饰 | N-glycosylation is required for efficient cell surface expression, and protection from proteolytic degradation. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG66890 anti-SLC26A3 / DRA antibody WB image
Western blot: 293 and HeLa cell lysates stained with ARG66890 anti-SLC26A3 / DRA antibody.
