ARG44524

anti-SLC25A25 / APC3 antibody

anti-SLC25A25 / APC3 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes SLC25A25 / APC3
反应物种 Hu, Ms, Rat
应用 FACS, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 SLC25A25 / APC3
抗原物种 Human
抗原 Human SLC25A25 / APC3 recombinant protein
偶联标记 Un-conjugated
別名 SLC25A25; Solute Carrier Family 25 Member 25 ; KIAA1896; PCSCL; MCSC; Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 25; Mitochondrial Ca(2+)-Dependent Solute Carrier Protein 3; Short Calcium-Binding Mitochondrial Carrier Protein 2; Mitochondrial Adenyl Nucleotide Antiporter SLC25A25; Mitochondrial ATP-Mg/Pi Carrier Protein 3; SCAMC2; Calcium-Binding Mitochondrial Carrier Protein SCaMC-2; Short Calcium-Binding Mitochondrial Carrier 2; Small Calcium-Binding Mitochondrial Carrier 2; SCAMC-2; SCaMC-2; MCSC3; APC3

应用说明

应用建议
应用 推荐稀释比
FACS1-3 µg/1x10^6
IHC-P2-5 µg/ml
WB0.25-0.5 µg/ml
应用说明 The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified with Immunogen.
缓冲液 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂 0.05% Sodium azide
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 114789 Human SLC25A25

GeneID: 227731 Mouse SLC25A25

GeneID: 246771 Rat SLC25A25

基因名称 SLC25A25
全名 Solute Carrier Family 25 Member 25
背景介绍 The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene.
生物功能 Electroneutral antiporter that most probably mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it could have a broader specificity for adenyl nucleotides. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways.
细胞定位 Membrane, Mitochondrion, Mitochondrion inner membrane
预测分子量 53 kDa

检测图片 (5) Click the Picture to Zoom In

  • ARG44524 anti-SLC25A25 / APC3 antibody IHC-P image

    Immunohistochemistry: Human prostate cancer stained with ARG44524 anti-SLC25A25 / APC3 antibody at 2 μg/mL dilution.

  • ARG44524 anti-SLC25A25 / APC3 antibody WB image

    Western blot: K562, SiHa, Jurkat and MCF-7 stained with ARG44524 anti-SLC25A25 / APC3 antibody at 0.5 μg/mL dilution.

  • ARG44524 anti-SLC25A25 / APC3 antibody FACS image

    Flow Cytometry: JK stained with ARG44524 anti-SLC25A25 / APC3 antibody at 1 μg/10^6 cells dilution.

  • ARG44524 anti-SLC25A25 / APC3 antibody WB image

    Western blot: Rat liver stained with ARG44524 anti-SLC25A25 / APC3 antibody at 0.5 μg/mL dilution.

  • ARG44524 anti-SLC25A25 / APC3 antibody WB image

    Western blot: RAW264.7 stained with ARG44524 anti-SLC25A25 / APC3 antibody at 0.5 μg/mL dilution.