ARG42751
anti-SLC25A12 antibody
anti-SLC25A12 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SLC25A12 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SLC25A12 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-180 of Human SLC25A12 (NP_003696.2). |
| 偶联标记 | Un-conjugated |
| 別名 | AGC1; ARALAR; Mitochondrial aspartate glutamate carrier 1; Calcium-binding mitochondrial carrier protein Aralar1; Solute carrier family 25 member 12 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | U-87MG | ||||
| 实际分子量 | ~ 70 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O75746 Human Calcium-binding mitochondrial carrier protein Aralar1 Swiss-port # Q8BH59 Mouse Calcium-binding mitochondrial carrier protein Aralar1 |
|---|---|
| 基因名称 | SLC25A12 |
| 全名 | solute carrier family 25 (aspartate/glutamate carrier), member 12 |
| 背景介绍 | This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012] |
| 生物功能 | Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane (PubMed:11566871, PubMed:25410934). May have a function in the urea cycle (PubMed:11566871). [UniProt] |
| 细胞定位 | Mitochondrion inner membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 75 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG42751 anti-SLC25A12 antibody WB image
Western blot: 25 µg of U-87MG cell lysate stained with ARG42751 anti-SLC25A12 antibody at 1:3000 dilution.
