ARG40381
anti-SLC22A12 / URAT1 antibody
anti-SLC22A12 / URAT1 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SLC22A12 / URAT1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SLC22A12 / URAT1 |
| 抗原物种 | Human |
| 抗原 | Recombinant full length protein of Human SLC22A12 / URAT1. |
| 偶联标记 | Un-conjugated |
| 別名 | Organic anion transporter 4-like protein; Urate anion exchanger 1; OAT4L; URAT1; Renal-specific transporter; Solute carrier family 22 member 12; RST |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 70 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SLC22A12 |
| 全名 | solute carrier family 22 (organic anion/urate transporter), member 12 |
| 背景介绍 | The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] |
| 生物功能 | Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Note=Detected in the luminal membrane of the epithelium of renal proximal tubules. [UniProt] |
| 预测分子量 | 60 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG40381 anti-SLC22A12 / URAT1 antibody WB image
Western blot: HeLa, HepG2, Mouse kidney and Rat kidney lysates stained with ARG40381 anti-SLC22A12 / URAT1 antibody.
