ARG46492

anti-SLC1A7 antibody

anti-SLC1A7 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes SLC1A7
反应物种 Hu, Ms
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 SLC1A7
抗原物种 Human
抗原 A 14 amino acid synthetic peptide within the last 50 amino acids of human SLC1A7.
偶联标记 Un-conjugated
別名 SLC1A7; solute carrier family 1 (glutamate transporter), member 7; Solute carrier family 1 (glutamate transporter) member 7; AAAT; excitatory amino acid transporter 5; EAAT5

应用说明

应用建议
应用 推荐稀释比
IHC-PAssay-dependent
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 52 kDa

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -542°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 242607 Mouse SLC1A7

GeneID: 6512 Human SLC1A7

Swiss-port # O00341 Human Excitatory amino acid transporter 5

Swiss-port # Q8JZR4 Mouse Excitatory amino acid transporter 5

基因名称 SLC1A7
全名 solute carrier family 1 (glutamate transporter), member 7
背景介绍 Enables glutamate:sodium symporter activity. Involved in neurotransmitter uptake. Predicted to be located in photoreceptor cell terminal bouton. Predicted to be active in glutamatergic synapse; postsynaptic membrane; and presynaptic membrane. [provided by Alliance of Genome Resources, Jul 2025]
生物功能 Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:9108121). Acts primarily as an inhibitory glutamate-gated chloride channel being a major inhibitory presynaptic receptor at mammalian rod bipolar cell axon terminals. Glutamate binding gates a large Cl(-) conductance that mediates inhibition, affecting visual processing in the retina (By similarity). [UniProt]
细胞定位 Cell membrane. [UniProt]
预测分子量 17, 52, 62, 68 kDa
翻译后修饰 Glycoprotein. [UniProt]