ARG58770
anti-SLC16A3 / MCT4 antibody
anti-SLC16A3 / MCT4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SLC16A3 / MCT4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SLC16A3 / MCT4 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 371-465 of Human SLC16A3 / MCT4 (NP_004198.1). |
| 偶联标记 | Un-conjugated |
| 別名 | MCT 4; MCT 3; Solute carrier family 16 member 3; Monocarboxylate transporter 4; MCT4; MCT-3; MCT-4; MCT3 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HT1080 | ||||||
| 实际分子量 | 49 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SLC16A3 |
| 全名 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| 背景介绍 | Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]). [supplied by OMIM, Mar 2008] |
| 生物功能 | Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity). [UniProt] |
| 细胞定位 | Cell membrane, Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 49 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58770 anti-SLC16A3 / MCT4 antibody WB image
Western blot: 25 µg of HT1080 cell lysate stained with ARG58770 anti-SLC16A3 / MCT4 antibody at 1:1000 dilution.
