ARG10599
anti-SLC10A1 antibody
anti-SLC10A1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
参考文献1
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SLC10A1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SLC10A1 |
| 抗原物种 | Human |
| 抗原 | aa. 141-154 (YSRGIYDGDLKDKV) of Human SLC10A1. |
| 偶联标记 | Un-conjugated |
| 別名 | Sodium/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; NTCP |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | Antigen Retrieval for IHC-P: steamed with pH 6 citrate buffer. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.025% Sodium azide and 2.5% BSA. |
| 抗菌剂 | 0.025% Sodium azide |
| 稳定剂 | 2.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SLC10A1 |
| 全名 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| 背景介绍 | The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011] |
| 生物功能 | The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. [UniProt] |
| 预测分子量 | 38 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG10599 anti-SLC10A1 antibody IHC-P image
Immunohistochemistry: Human liver cancer tissue stained with ARG10599 anti-SLC10A1 antibody.
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ARG10599 anti-SLC10A1 antibody WB image
Western blot: 1) Rat liver and 2) Rat brain lysate stained with ARG10599 anti-SLC10A1 antibody.
文献引用
Integrated 16 S rRNA gene sequencing and serum metabolomics approaches to decipher the mechanism of Qingre Lidan decoction in the treatment of cholestatic liver injury
WB / Mouse
