ARG22658
anti-SLA Class II DR antibody [2E9/13]
anti-SLA Class II DR antibody [2E9/13] for Flow cytometry,IHC-Frozen sections,Immunoprecipitation and Bovine,Pig
概述
| 产品描述 | Mouse Monoclonal antibody [2E9/13] recognizes SLA Class II DR This antibody recognizes SLA DR molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells. Mouse anti Pig SLA Class II DR antibody, clone 289/13 reacts with lymphocytes from all outbred and miniature pigs so far tested, suggesting that it recognizes a monomorphic determinant of Porcine SLA DR. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR. Mouse anti Pig SLA class II Dr, clone 2E9/13 immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labelled Porcine peripheral blood mononuclear cells. Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and staphylococcal enterotoxin B (Bullido et al. 1997). |
|---|---|
| 反应物种 | Bov, Pig |
| 应用 | FACS, IHC-Fr, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 2E9/13 |
| 同位型 | IgG2b |
| 靶点名称 | SLA Class II DR |
| 抗原物种 | Pig |
| 抗原 | Porcine monocytes. |
| 偶联标记 | Un-conjugated |
| 別名 | SLA-DRA1; SLA-DRA2; SLA-DR-alpha |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10 µl of the suggested working dilution to 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | SLA-DRA |
|---|---|
| 全名 | MHC class II DR-alpha |
检测图片 (1) Click the Picture to Zoom In
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ARG22658 anti-SLA Class II DR antibody [2E9/13] FACS image
Flow Cytometry: Pig peripheral blood lymphocytes stained with ARG22658 anti-SLA Class II DR antibody [2E9/13] followed by Goat anti-Mouse IgG (FITC).
