ARG54660
anti-SIRT4 antibody
anti-SIRT4 antibody for ELISA,Western blot and Human,Mouse,Rat
Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Chicken Polyclonal antibody recognizes SIRT4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, WB |
| 宿主 | Chicken |
| 克隆 | Polyclonal |
| 同位型 | IgY |
| 靶点名称 | SIRT4 |
| 抗原 | Synthetic peptide (17 aa) within aa. 80-130 of Human SIRT4. |
| 偶联标记 | Un-conjugated |
| 別名 | SIR2L4; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; SIR2-like protein 4; EC 3.5.1.-; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; EC 2.4.2.-; Regulatory protein SIR2 homolog 4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Human Liver Tissue Lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8R216 Mouse NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Swiss-port # Q9Y6E7 Human NAD-dependent protein lipoamidase sirtuin-4, mitochondrial |
|---|---|
| 基因名称 | SIRT4 |
| 全名 | sirtuin 4 |
| 背景介绍 | SIRT4 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion. | |
| 研究领域 | Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 35 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG54660 anti-SIRT4 antibody WB image
Western blot: human liver tissue lysate stained with ARG54660 anti-SIRT4 antibody at 1 μg/ml.
