ARG46478
anti-SIK2 antibody
anti-SIK2 antibody for Western blot,ICC/IF and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SIK2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SIK2 |
| 抗原物种 | Human |
| 抗原 | A 16 amino acid synthetic peptide within the last 50 amino acids of human SIK2. |
| 偶联标记 | Un-conjugated |
| 別名 | SIK2; SNF1LK2; Serine/threonine-protein kinase SIK2; QIK; LOH11CR1I; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; EC 2.7.11.1; Serine/threonine-protein kinase SNF1-like kinase 2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8CFH6 Mouse Serine/threonine-protein kinase SIK2 Swiss-port # Q9H0K1 Human Serine/threonine-protein kinase SIK2 |
|---|---|
| 基因名称 | SIK2 |
| 全名 | salt-inducible kinase 2 |
| 生物功能 | Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. [UniProt] |
| 预测分子量 | 104 kDa |
| 翻译后修饰 | Phosphorylated at Thr-175 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Acetylation at Lys-53 inhibits kinase activity. Deacetylated by HDAC6. [UniProt] |
