ARG44520
anti-SHKBP1 antibody
anti-SHKBP1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SHKBP1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SHKBP1 |
| 抗原物种 | Human |
| 抗原 | Human SHKBP1 recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | SHKBP1; SH3KBP1 Binding Protein 1; PP203; Sb1; SH3KBP1-Binding Protein 1; SETA-Binding Protein 1; SB1 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SHKBP1 |
| 全名 | SH3KBP1 Binding Protein 1 |
| 背景介绍 | Enables identical protein binding activity. Predicted to be involved in positive regulation of epidermal growth factor receptor signaling pathway. Predicted to be located in lysosome. |
| 生物功能 | Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation. |
| 细胞定位 | Lysosome |
| 预测分子量 | 76 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein |
检测图片 (4) Click the Picture to Zoom In
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ARG44520 anti-SHKBP1 antibody IHC-P image
Immunohistochemistry: Human colon stained with ARG44520 anti-SHKBP1 antibody at 2 μg/mL dilution.
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ARG44520 anti-SHKBP1 antibody WB image
Western blot: A549, HEL whole and U251 stained with ARG44520 anti-SHKBP1 antibody at 0.5 μg/mL dilution.
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ARG44520 anti-SHKBP1 antibody FACS image
Flow Cytometry: A549 stained with ARG44520 anti-SHKBP1 antibody at 1 μg/10^6 cells dilution.
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ARG44520 anti-SHKBP1 antibody IHC-P image
Immunohistochemistry: Human liver cancer stained with ARG44520 anti-SHKBP1 antibody at 2 μg/mL dilution.
